Louisville beats Duke 85-63 to reach Final Four

Louisville's Peyton Siva, left, and Chane Behanan, celebrate following their 85-63 win over Duke in the Midwest Regional final in the NCAA college basketball tournament, Sunday, March 31, 2013, in Indianapolis. Behanan was wearing the jersey of teammate Kevin Ware (5) who was injured during the game. (AP Photo/Darron Cummings)

Louisville's Peyton Siva, left, and Chane Behanan, celebrate following their 85-63 win over Duke in the Midwest Regional final in the NCAA college basketball tournament, Sunday, March 31, 2013, in Indianapolis. Behanan was wearing the jersey of teammate Kevin Ware (5) who was injured during the game. (AP Photo/Darron Cummings)

Louisville players huddle as guard Kevin Ware is treated for an injury during the first half of the Midwest Regional final against Duke in the NCAA college basketball tournament, Sunday, March 31, 2013, in Indianapolis. (AP Photo/Michael Conroy)

Louisville players celebrate following their 85-63 win over Duke in the Midwest Regional final in the NCAA college basketball tournament, Sunday, March 31, 2013, in Indianapolis. (AP Photo/Michael Conroy)

Louisville forward Montrezl Harrell (24) blocks a shot by Duke forward Mason Plumlee during the first half of the Midwest Regional final in the NCAA college basketball tournament, Sunday, March 31, 2013, in Indianapolis. (AP Photo/Darron Cummings)

Louisville guard Peyton Siva (3) goes up with a shot against Duke guard Quinn Cook (2) during the first half of the Midwest Regional final in the NCAA college basketball tournament, Sunday, March 31, 2013, in Indianapolis. (AP Photo/Michael Conroy)

INDIANAPOLIS (AP) ? Crying and shaken by the sight of Kevin Ware writhing on the court, his right leg splintered, Rick Pitino and his Louisville players had no idea how they were going to pull it together with a half still left to play and a Final Four berth on the line.

Ware showed them the way.

"I don't think we could have gathered ourselves ? I know I couldn't have ? if Kevin didn't say over and over again, 'Just go win the game,'" Pitino said. "I don't think we could have gone in the locker room with a loss after seeing that. We had to gather ourselves. We couldn't lose this game for him.

"We just couldn't."

With Russ Smith, Peyton Siva and Gorgui Dieng leading the way, the Cardinals finally shook off their grief early in the second half, erupting for a 13-2 run that Duke was powerless to answer. The 85-63 victory clinched a second straight trip to the Final Four for the top-seeded Cardinals, who are determined to win it all for Ware, a New York City native who moved to the Atlanta area for high school.

The Cardinals (33-5) will play Wichita State in the national semifinals next Saturday. The ninth-seeded Shockers (30-8) added to their streak of upsets with a 70-66 victory over Ohio State on Saturday night.

As the final seconds ticked down, Ware's best friend on the team, Chane Behanan, put on the guard's No. 5 jersey and stood at the end of the bench, screaming. Cardinals fans chanted "Kevin Ware! Kevin Ware!"

"We talked about it every timeout, 'Get Kevin home,'" Pitino said.

Smith finished with 23 points and earned Most Outstanding Player honors for the Midwest Region. Siva added 16 while Dieng had 14 points and 11 rebounds.

Mason Plumlee had 17 points and 12 rebounds for Duke. But the Blue Devils (30-6) couldn't overcome a poor start by Seth Curry, who scored all 12 of his points in the second half, or their foul trouble.

"I thought we had a chance there, and then, boom," coach Mike Krzyzewski said. "That's what they do to teams. They can boom you."

This was the first time Pitino and Krzyzewski had met in the regional finals since that 1992 classic that ended with Christian Laettner's improbable buzzer-beater, a game now considered one of the best in NCAA tournament history.

This game will be remembered, too, but for a very different ? and much more somber ? reason.

With 6:33 left in the first half, Ware, who has played a key role in Louisville's 14-game winning streak, jumped to try and block Tyler Thornton's 3-point shot. When he landed, Ware's right leg snapped midway between his ankle and knee, the bone skewing almost at a right angle. Ware dropped to the floor right in front of the Louisville bench and, almost in unison, his teammates turned away in horror. Thornton grimaced, putting his hand to his mouth as he turned around.

"I heard it and then I seen what happened, (the bone) come out," Smith said. "I immediately just, like, fell. I almost didn't feel nothing."

Pitino went to help Ware up and then saw the leg, which broke in two places.

"I literally almost threw up," Pitino said, his voice catching. "Then I just wanted to get a towel to get it over that. But all the players came over and saw it."

Louisville forward Wayne Blackshear fell to the floor and Behanan looked as if he was going to be sick on the court, kneeling on his hands and feet. Luke Hancock patted Ware's chest as doctors worked on the sophomore and Smith walked away, pulling his jersey over his eyes. The arena was silent, and several fans wept and bowed their heads.

Pitino had tears in his eyes as he tried to console his players. Dieng draped an arm around the shoulders of Smith, who repeatedly wiped at his eyes and shook his head.

"It was really hard for me to pull myself together," Smith said. "I didn't ever think in a million years I would ever see something like that. And that it happened, especially, to a guy like Kevin Ware, I was completely devastated."

As the Cardinals (33-5) gathered at halfcourt to try and regroup before play resumed, Pitino called them over to the sideline, saying Ware wanted to talk to them before he left.

"Basically, the bone popped out of the skin. It broke in two spots," Pitino said. "Remember the bone is six inches out of his leg, and all he's yelling is 'Win the game, win the game.' I've never seen anything like that."

Added Siva, "He told us countless times: 'Just go win this game for me. Just go win this game. Don't worry about me, I'm fine. Just go win this game.' I don't know how he did it. I don't know how he got strength to do it, but he told us to go out there and win."

News of the injury dominated social media. Joe Theismann, whose NFL career ended with a horrific broken leg, said on Twitter, "Watching Duke/ Louisville my heart goes out to Kevin Ware."

Pitino wiped away tears as Ware, whom Smith described as the Cardinals' "little brother" was wheeled off the court. Surgeons reset his leg and inserted a rod in his right tibia during a 2-hour operation at Methodist Hospital. Ware is expected to remain in Indianapolis until at least Tuesday, and Pitino said he, his son Richard and the Cardinals' equipment manager planned to visit the player later Sunday night and again Monday morning.

"He'll come back," Pitino said. "We'll get Kevin back as good as new."

But when play resumed, it was clear the Cardinals' minds were elsewhere. They missed four of their next five shots along with two free throws, and were uncharacteristically sloppy. But they regrouped after a timeout, with Smith's finger roll sparking a 12-6 run to finish the half that gave them a 35-32 lead.

Smith picked up where he left off at the start of the second half, making all three free throws after being fouled on a 3-point attempt to give Louisville a 38-32 lead, its largest of the game to that point.

But just as he did against Michigan State, Curry got hot after halftime, making two 3s in the first three minutes. A Plumlee dunk tied the game at 42.

That, however, was all Louisville needed.

Clawing for every rebound, diving on the floor for loose balls and cranking the intensity up even higher on their ferocious defense, the Cardinals were not going to lose.

And everyone, Duke included, knew it.

This was only the second time the Blue Devils have reached the regional finals and failed to make it to the Final Four. The only other time? In 1998, when the Blue Devils lost to eventual national champion Kentucky.

"We got beat by a better team," Krzyzewski said.

Smith made a layup. Siva had a nice jumper at the top of the key, and then followed with a layup. Just like that, Louisville was off. Siva had seven points during the run, which was only halted by a timeout. But Dieng kept it rolling with a jumper and a tip-in. After Plumlee made a pair of free throws, Hancock made a 3 and the roof of the Lucas Oil Stadium nearly blew off.

"When Kevin went down, it was devastating for all of us," Siva said. "We just came together and Kevin Ware really was the reason why we pulled this game out.

"Everybody on the team just wanted to step up for him. For us to show that focus and that determination, we just tried to do it for him."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2013-03-31-NCAA-Duke-Louisville/id-b6a4b0d4fe6741ca8673339e7bf9ab38

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Friday Night Lights and Leather Pants

Author Buzz Bissinger in 2011

Photo by Michael Loccisano/Getty Images

Every weekend, Longform shares a collection of great stories from its archive with Slate. For daily picks of new and classic nonfiction, check out Longform or follow @longform on Twitter. Have an iPad? Download Longform?s app to read the latest picks, plus features from 70 of the world?s best magazines, including Slate.

Assuming you were anywhere near the Internet this week, you probably heard that Buzz Bissinger, the Pulitzer-Prize winner and author of Friday Night Lights, has spend more than $600,000 on expensive, and often bizarre, leather clothing. Read ?My Gucci Addiction,? his sprawling, confessional essay published Tuesday by GQ, then read these amazing pre-Gucci Bissinger stories:

Friday Night Lights
Sports Illustrated ? September 1990

Before the show, before the movie, there was Bissinger?s tale of the 1988 Permian Panther football team and the small West Texas city of Odessa, where he lived with a family for a year.

?The faithful sat on little stools of orange and blue under the merciless lights of the high school cafeteria, but the spartan setting didn't bother them a bit. Had the booster club's Watermelon Feed been held inside the county jail, or on a sinking ship, or on the side of a craggy mountain, these fans still would have flocked there.

?Outside, the August night was cool and serene, with just a wisp of West Texas wind. Inside, there was a sense of excitement and also relief, for the waiting was basically over?no more sighs of longing, no more awkward groping to fill up the empty spaces of time with golf games and thoroughly unsatisfying talk about baseball. Tonight the boys of Permian High School in Odessa would come before the crowd, one by one, to be introduced. And in less than two weeks, on the first Friday night in September, the march to state?to the Texas high school championship finals?would begin with the first game of the season."

The Killing Trail
Vanity Fair ? February 1995?

The story of eight gay men in Texas murdered by teenage boys.

?On a frigid night in east Texas in 1993, just a few weeks before Christmas, a 23-year-old gay man named Nicholas West is abducted from Bergfeld Park in Tyler. He is taken to a hilly isolated area of red clay nicknamed the Pits, a place where pleas for mercy evaporate under the cold shine of the stars. He is punched, kicked and slapped across the face with a .357 magnum. When he falls to the ground, utterly alone and helpless in that marrow of darkness, blood oozing out of his eye, his three abductors gather around him with their arsenal of loaded weapons. Then the shooting begins?so many entrance and exit wounds that by the time of the autopsy, West?s body looks like a stickpin doll. There are at least 9 bullets, the first in the abdomen, then several through the arms and hands, then at least 4 up the back in a pattern as neatly spaced as the buttons on a shirt. Eight shots at that point, but Nicholas is still alive, his breath reduced to a tiny gurgle, until the final shot is fired into the back of his head. Then he is left on that field of red clay, face down, without shoes or pants, his arms by his sides and his legs spread apart like those of a sleeping child, the bottom of his socks red from the clay, and his underwear soiled by a fear that none of us could ever know.

?After the murder, one of the killers rides around in the red Mazda truck that West had driven to the park that night. Impressed by the power of the truck, he squeals the tires the way the drag racers do it. Then he goes on over to the laundromat on Troup Highway in Tyler to do a load of wash.?

Shattered Glass
Vanity Fair ? September 1998

At 25, Stephen Glass was a reporter wunderkind, regularly filing incredible pieces for the largest magazines. When suspicion fell on his sources, things started to really get strange. It wasn?t just sources and organizations he was inventing, but whole stories.

?For those two and a half years, the Stephen Glass show played to a captivated audience; then the curtain abruptly fell. He got away with his mind games because of the remarkable industry he applied to the production of the false backup materials which he methodically used to deceive legions of editors and fact checkers. Glass created fake letterheads, memos, faxes, and phone numbers; he presented fake handwritten notes, fake typed notes from imaginary events written with intentional misspellings, fake diagrams of who sat where at meetings that never transpired, fake voice mails from fake sources. He even inserted fake mistakes into his fake stories so fact checkers would catch them and feel as if they were doing their jobs. He wasn?t, obviously, too lazy to report. He apparently wanted to present something better, more colorful and provocative, than mere truth offered.?

Gone Like the Wind
Vanity Fair ? August 2007

After one of the most decisive wins in Kentucky Derby history, Barbaro broke his leg at the Preakness, ending a promising career and beginning a herculean effort to save his life.

?But the problem for Gretchen Jackson was she did fall in love with a horse. She fell in love with him because when he was in his element on the racecourse there were moments he ran with such joy and abandon that he actually flew, all four feet off the ground. She fell in love with him because of the way he soldiered on after he was tragically hurt in the Preakness Stakes in May 2006, his sense of self so intact that he bit one veterinarian smack on the butt and ran a masseuse out of the stall. She fell in love with him because of the gleam in his eyes, still bright, during those dark days in July 2006 when both his rear lower limbs became a medical nightmare, and she wrote in the private journal she kept:

?It's not good. Oh my God I am so concerned. Dear Lord we cannot let the bright light fade, flicker, die. We must conquer. Where are you God in my suffering? Are you holding my hands showing me full moons and breezy nights? Yes Lord, they are magnificent but my heart is looking at Barbaro. That is not the horse that won the derby.

?She fell in love with him because of the way he was trying to communicate, Don't give up on me yet. She fell in love with him because of the way he rallied after that. And then she fell in love with him because of the way he died.?

To Bean or Not to Bean
Sports Illustrated ? March 2005

On the retaliation ethics of baseball.

?But once he is convinced of malicious intent, deciding how to respond is just as hard--an agony even worse for him than losing. ?The responsibilities and the consequences are huge,? La Russa says. Thrown baseballs have ended careers; one player, Cleveland Indians shortstop Ray Chapman, died as a result of a beaning in 1920. In meetings with pitchers during spring training, La Russa issued clear guidelines: Any message had to be aimed at the ribs or below. Nothing above the shoulders would be tolerated.

?La Russa knows that over the years he has gained a reputation for being vengeful at times when vengeance did not seem necessary. He is also known as something of a headhunter himself, but La Russa asserts that he has never told a pitcher to throw at a hitter simply because the batter was too dangerous and needed to be quieted down. ?If a guy is hitting good against us,? he says, ?I have never told a pitcher to go out and drill him. I have said, 'Pitch the guy tough, pitch the guy different.' If a pitcher does something on his own, I will take him out. You can pitch a hitter inside. You can try to open up the plate on him, get him to speed up the bat. But you do not drill him.? ?

Buzz Bissinger: A Savior for the City
Sandy Hingston ? Philadelphia Weekly ? May 2010

A profile of Bissinger as he returned to his old stomping grounds, the Philadelphia Inquirer.

?In person, Buzz vacillates between prickly and pacific. There?s a pattern to how he answers questions; he starts out calm and rational and then shifts into irate gear. ?I am opinionated, passionate,? he allows. ?I have strong feelings.? And he vents them, in conversation and in his writing. He?s furious at Philadelphia politicians, at patronage, at the proposed soda tax, at his fellow Inquirer columnists, who never tackle local issues and don?t even live in the city, especially Rick Santorum, who so far as Buzz can tell dwells ?in a world all his own.? That?s the simple explanation for why he said yes when Inky editor-in-chief Bill Marimow invited him back, 20-plus years after he last set foot in the newsroom. ?There was a void, a vacuum,? Buzz says. ?Nothing ever changes in this city. I knew all these guys. No one was holding them accountable.? So Buzz has taken on all comers. ?I am tired of defense attorneys using loopholes that have nothing to do with guilt or innocence,? he wrote in December, ?and I wonder how these suckerfish can sleep at night knowing that all they have done is increase the already unconscionable probability that an innocent citizen will be robbed or even killed.? He skewered ex-mayor John Street: ?[N]ever have I seen a human being who went so unfortunately out of his way to be remote, resistant, removed, repulsed by the sight of others.? And he called the mighty out by name; in March, he eviscerated Foxwoods? Lew Katz, Ed Snider, and Ron Rubin, saying they had ?the swag and swagger that come with always getting what you want because of who you know.?

? ?That?s what the assignment is,? says Buzz?s old friend David Cohen. ?To be tough and provocative, and advance the civic discussion of the city.? But Buzz?s ?Half Empty? column isn?t just a platform from which he can speak ? well, scream ? truth to power. There?s also the matter of Steve Lopez. Lopez wrote a column for the Inquirer back in the day, and though he moved on to Time Inc. in the ?90s and the L.A. Times the in 2001, ?The Inquirer still misses Steve Lopez,? says PR kingpin Larry Ceisler, also a longtime friend of Buzz. Buzz allows that Lopez is one reason he came back, but frames it differently: ?I want to prove he isn?t the only columnist the Inquirer ever had. I want to eradicate the memory of Steve Lopez. Because I?m a competitive little shit.? ?

Have a favorite piece that we missed? Leave the link in the comments or tweet it to @longform. For more great writing, check out Longform?s complete archive.

Source: http://feeds.slate.com/click.phdo?i=b2af293671418be025dce10a23291616

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Egypt issues arrest warrant for TV satirist

FILE - In this Saturday Dec. 8, 2012 file photo, Egyptian TV host Bassem Youssef addresses attendants at a gala dinner party in Cairo, Egypt. Egypt?s state news agency said Saturday, March 30, 2013 that the public prosecution office has issued an arrest warrant against a popular TV satirist for allegedly insulting Islam and the country?s president. The warrant issued Saturday is the latest in a series of legal action against Youssef, known as Egypt?s Jon Stewart. The warrant comes amid a widening crackdown against opposition figures, driving fears over freedoms of expression and assembly. (AP Photo/Ahmed Omar, File)

FILE - In this Saturday Dec. 8, 2012 file photo, Egyptian TV host Bassem Youssef addresses attendants at a gala dinner party in Cairo, Egypt. Egypt?s state news agency said Saturday, March 30, 2013 that the public prosecution office has issued an arrest warrant against a popular TV satirist for allegedly insulting Islam and the country?s president. The warrant issued Saturday is the latest in a series of legal action against Youssef, known as Egypt?s Jon Stewart. The warrant comes amid a widening crackdown against opposition figures, driving fears over freedoms of expression and assembly. (AP Photo/Ahmed Omar, File)

CAIRO (AP) ? Egypt's state prosecutors ordered the arrest Saturday of a popular television satirist for allegedly insulting Islam and the country's leader, in a move that government opponents say is aimed at silencing critics of Islamist President Mohammed Morsi.

The arrest warrant for against Bassem Youssef, who has come to be known as Egypt's Jon Stewart, followed an order earlier this week by the country's top prosecutor to arrest five prominent pro-democracy activists in what the opposition has characterized as a widening campaign against dissent.

The acceleration in legal action targeting protesters, activists and critics comes against a backdrop of continued unrest in the country. Political compromise between the well-organized Islamists in power and their vocal liberal and largely secular critics remains elusive, while the country's economy is in near free fall, which has increasingly fueled popular frustration.

The opposition charges that Morsi, in office for nine months, and the Brotherhood have failed to tackle any of the nation's most pressing problems and are trying to monopolize power, breaking their promises of inclusiveness. Morsi blames the country's woes on nearly three decades of corruption under his predecessor, Hosni Mubarak, and accuses the opposition of stoking unrest for political gain.

The warrant against Youssef is the latest in a series of legal actions against the comedian, whose widely-watched weekly show, "ElBernameg" or "The Program," has become a platform for lampooning the government, opposition, media and clerics. He has also used his program to fact-check politicians.

The fast-paced show has attracted a wide viewership, while at the same time earning itself its fair share of detractors. Youssef has been a frequent target of lawsuits, most of them brought by Islamist lawyers who have accused him of "corrupting morals" or violating "religious principles."

Prosecutor Mohammed el-Sayed Khalifa told Al-Ahram online that he has heard 28 plaintiffs accusing Youssef of insulting Islam, mocking prayers, and "belittling" Morsi in the eyes of the world and his own people.

In one episode of the show, Youssef mocks former militants who are now part of the mainstream political scene in Egypt. At a recent rally, some former radicals who were imprisoned for taking part in the assassination of late President Anwar Sadat in 1981, accused the opposition of using violence at anti-Morsi protests.

In the program, Youssef ridicules an Islamist who said the militants had repented by fasting for three months for mistakenly killing others with Sadat.

"What a message," Youssef says. "Anyone can form a group in the name of religion, assassinate in the name of religion, and then oops! Repent and fast for three months, and it will too pass in the name of religion."

The comedian has faced several court cases in the past accusing him of insulting Morsi. One of Youssef's attorneys, Gamal Eid, said however that this is the first time an arrest warrant has been issued for the comedian.

In a post on his official Twitter account, Youssef said he will hand himself in to the prosecutor's office Sunday. He then added, with his typical sarcasm: "Unless they kindly send a police van today and save me the transportation hassle."

Eid said the warrant fits into a widening campaign against government critics, media personalities, and activists, saying "the prosecution has become a tool to go after the regime's opposition and intimidate it."

A call to a top aide to the country's chief prosecutor, Hassan Yassin, for comment went unanswered.

The other recent arrest warrants for five high-profile activists were issued over allegations that they instigated violence last week near the Brotherhood's headquarters in Cairo, where nearly 200 people were injured in clashes between anti-government protesters and supporters of the Brotherhood, from which Morsi hails.

Morsi responded by harshly criticizing his opponents, calling them hired thugs out to derail Egypt's democracy. The Brotherhood also blamed privately-owned media for fanning the violence.

The criticism was followed by a two-day protest by dozens of Islamists outside the studios of TV networks critical of Morsi. The protesters pelted police and prevented some talk show hosts and guests from entering or leaving the complex.

The New York-based Committee to Protect Journalists called the escalation of anti-press "rhetoric" by Morsi and his supporters and the sit-in outside the media city were "deeply troubling."

The series of prosecutions and arrest warrants come amid a legal challenge to the chief prosecutor, Talaat Abdullah, whose appointment by Morsi last year was declared void by a court ruling earlier this week.

On Saturday, Abdullah said he will appeal the court ruling, saying it is "in violation of the constitution and the law," Egypt's state news agency reported. The decision signals a protracted legal battle is likely to ensue, further confusing the legal scene in Egypt.

In the Mediterranean port city of Alexandria, an Egyptian rights group said Saturday that police detained 13 people, including five lawyers, and accused them of assaulting police. The arrests inside the police station mark a rare instance in which lawyers face potential criminal charges.

The Haqanya Center for Rights said the 13 are accused of insulting security officials, attempting to free other detainees at the police station and illegal assembly.

The arrests prompted an angry response from lawyers at Cairo's Bar Association, who demanded an apology from the police.

Those detained include prominent lawyer and pro-democracy activist Mahienour el-Masry. Several dozen Cairo protesters held a rally outside the chief prosecutor's office, dismissing his orders as void, locking up the gates to his office with chains and demanding the release of the lawyers and activists.

Mohammed Abdel-Aziz, an attorney, said the lawyers and activists were beaten and assaulted at the station, where they had been since Friday to represent three opposition members reportedly detained and taken to the police by members of a political party affiliated with the Brotherhood.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2013-03-30-Egypt/id-f27c3adb09624ad6892b128d6654ec0c

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Toronto's Premier Online Marketing and SEO Company Numero ...

Numero Uno Web Solutions (NumeroUnoWeb.com), a fast-growing global Internet marketing firm that caters to small- and mid-sized business-to-consumer companies, is pleased to announce its top social media marketing strategies for e-commerce web sites.

Toronto, Ontario (PRWEB) March 30, 2013

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?Social media has revolutionized the way businesses market and communicate their brand, and it opens up an exciting new dimension in online marketing. But it takes more than a new Facebook page to succeed in the social media marketplace,? says Nadia Iaboni, Digital Solutions Manager at Numero Uno Web Solutions.

As the experts at Numero Uno Web Solutions note, in less than 10 years, social media sites like Facebook have evolved from simple meeting places into some of the most important online marketing and communication tools a small- and medium-sized business can utilize. Unlike traditional marketing channels, with social media, consumers are in control; sharing testimonials and brand experience, which can directly impact the way others spend their money. At the same time, thanks to social media, small- and medium-sized businesses have the opportunity to directly engage with their customers in real time.

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?To help a brand gain traction on social media sites and be more shareable, it?s more advantageous to provide entertaining, interesting blog posts, facts, videos, images, and infographics than it is a hard sales tactic,? adds Iaboni. ?Knowing an audience means creating relevant content that people care about. That?s why its important businesses tie the brand to content that users will want to pass along.?

?Posting fresh, interesting, shareable content on social media channels can help businesses become an authority in their field. By enhancing brand awareness, businesses can build trust and reinforce the company?s authority status. And, as a result, that business could be the first company a consumer thinks about when the need arises,? Iaboni concludes.

According to Numero Uno Web Solutions? top tips, effective social media marketing has to incorporate SEO with content strategy. Social media can be an excellent marketing channel, but only if it?s properly integrated with an SEO campaign. It doesn?t matter how many Facebook likes a company gets if it doesn?t translate into sales.

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Numero Uno Web Solutions is one of the top Internet marketing firms due to constant innovation and overall customer satisfaction. For more information on Numero Uno Web Solutions, and to discover how the company can help maximize your company?s search engine optimization and online presence, visit http://numerounoweb.com/sitescore/. Or call Numero Uno Web Solutions toll-free at 1-855-SEO-XPRT (1-855-736-9778).

For the original version on PRWeb visit: http://www.prweb.com/releases/prweb2013/3/prweb10584157.htm

Source: http://pressreleases.bloginteract.com/2013/03/torontos-premier-online-marketing-and-seo-company-numero-uno-web-solutions-announces-its-top-social-media-strategies-for-e-commerce-sites/

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90% Caesar Must Die

All Critics (41) | Top Critics (16) | Fresh (37) | Rotten (4)

There's barely a wasted moment in the film, which runs a brisk 76 minutes and contains no female roles.

There's an intensity and emotional accuracy to the performances that's just stunning, particularly Striano's Brutus, as he longs for death and release.

It's an arresting, playful and moving film ...

Prison theatricals are nothing new in the movies, but Caesar Must Die, a quasi-documentary featuring hardened convicts acting out Shakespeare's Julius Caesar, is in a class by itself.

Ranks among the most involving adaptations of Shakespeare ever put on screen ...

What works best is what's readily accessible, the startling power of performers who understand the drama all too well.

As they find issues and themes they can relate to, the action is never remotely static despite the frequent nature of the close-ups and the plastic sword.

The problem with the film, which somewhat inexplicably won the Golden Bear at Berlin last year, is that it scarcely transcends the basic novelty of its premise.

The juxtaposition of Shakespearean text and prison cell life is a particularly poignant one.

It is difficult to understand exactly where documentary ends and fiction begins, but the finale, again in colour, of the triumphant first night of the production can't fail to move.

It's never anything less than interesting, though I felt it didn't quite fulfil its potential, and the repetition of material at the beginning and end is disconcerting.

It is uncanny how Italy's film-makers keep failing to nail, or effectively to satirise, their country's strident political shortcomings.

Deeply felt melancholy lingers long after the credits roll.

Delivers a compelling and considered take on immemorial themes.

[It] has plenty of wit and punch, although compared to the best of the medium - Man On Wire, for instance - it sometimes comes off as guileless and clunky.

[An] inventive, urgent and humane prison drama, in which real-life Mafia and Camorra prisoners act in a version of Julius Caesar.

If you're looking for an adventurous thought-provoking film, "Caesar Must Die" more than fits the bill.

In just 76 minutes, the Taviani brothers treat us to a deeply affecting adaptation of this ancient play, embedded with even deeper meaning on account of its unconventional stars.

Here's an extraordinary melding of the actualities of modern man with his ancient past. Sadly, humankind hasn't made much progress when it comes to controlling its ambitious and testosterone-tinged impulses. Happily, human frailties make great art.

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Source: http://www.rottentomatoes.com/m/caesar_must_die_2012/

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Business Insider's Owen Thomas Is In Talks To Be The New Editor At ReadWrite

My old boss Owen Thomas is very close to becoming the new editor-in-chief at the SAY Media-owned tech site ReadWrite, according to sources with knowledge of the company. I'm hearing that it's not quite a done deal, but that it's looking very likely. Naturally, I called Owen to ask if this was the case, but he declined to comment. A SAY spokesperson told me, "There's obviously a lot of interest in ReadWrite. There are a lot of good candidates in the mix, and no one's been hired yet." (Just to reiterate ? I'm not saying he's been hired, just that the discussions are pretty far along.)

Source: http://feedproxy.google.com/~r/Techcrunch/~3/Aaycjhsnrlo/

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Calif. girl on school field trip struck by arrow

By Jeff Black, Staff Writer, NBC News

An 8-year-old ?girl on a school field trip to the University of California science museum in Berkeley was hit by an arrow while she played on a whale sculpture.

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UC Berkeley Police

Arrow that hit 8-year-old girl on Tuesday.

The girl, who was hit in the leg Tuesday, had to have the arrow surgically removed. She spent the night in the hospital and was released on Wednesday afternoon, according to NBCBayArea.com.

Who fired the arrow, which came from a crossbow, remains a mystery. Police were tracing the projectile's trajectory to determine where it came from, but have not located a suspect. It remained unclear if the arrow shooting was an accident or a malicious act.

Read more on NBCBayArea.com

The whale sculpture is located in a plaza outside the Lawrence Hall of Science. Other students in the area were taken inside after the girl was hit.

UC Berkeley does have an archery group, but its members practice on the other side of the campus.

Field trip chaperone Geoff Vassallo said the girl cried as she waited for an ambulance, but ?was a pretty brave little girl.?

Source: http://feeds.nbcnews.com/c/35002/f/653381/s/2a11fcc8/l/0Lusnews0Bnbcnews0N0C0Inews0C20A130C0A30C270C17491170A0Ecalif0Egirl0Eon0Eschool0Efield0Etrip0Estruck0Eby0Earrow0Dlite/story01.htm

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T-Mobile USA's new plans compared to competition

T-Mobile Chief Marketing Officer Mike Sievert holds brochures if competitors' plans as he speaks during a news conference, Tuesday, March 26, 2013 in New York. T-Mobile will start offering the iPhone 5 on April 12, filling what company CEO John Legere said was "a huge void" in its phone lineup. The company is currently the only major U.S. carrier not to offer Apple's popular smartphone. (AP Photo/Mary Altaffer)

T-Mobile Chief Marketing Officer Mike Sievert holds brochures if competitors' plans as he speaks during a news conference, Tuesday, March 26, 2013 in New York. T-Mobile will start offering the iPhone 5 on April 12, filling what company CEO John Legere said was "a huge void" in its phone lineup. The company is currently the only major U.S. carrier not to offer Apple's popular smartphone. (AP Photo/Mary Altaffer)

NEW YORK (AP) ? T-Mobile USA has revamped its pricing plans, the latest move in an industry that's still experimenting feverishly with various ways of luring customers and getting current ones to pay as much as possible. Here's how T-Mobile's gambit compares.

T-Mobile USA

The most significant change is that T-Mobile is breaking the cost of the phone away from the monthly service fee. Instead, the company will sell the phone on an installment. It's making a big deal out of the fact that it will no longer have two-year service contracts, but it's replacing them with two-year financing contracts. To buy an iPhone 5 from T-Mobile, you'll be putting $100 down and then paying $20 per month for two years to pay off the phone. That's on top of service fees that start at $50 per month for unlimited talk, text and 500 megabytes of data. An additional $10 per month gives you another 2 gigabytes of data. Add $20 instead, and you get unlimited data. If you leave T-Mobile within the two-year period, you'll still be charged $20 a month until the two-year contract runs out.

Pros: T-Mobile's plans are generally cheaper than the competition. If you've paid off your phone, your monthly bill declines. You can pay off the phone early if you want, with no penalty. You can also buy "unlocked" phones, or bring them over from AT&T, and get a good deal on monthly service. T-Mobile's "4G" service is relatively fast ? at least, faster than Sprint, in places where Sprint doesn't have LTE. T-Mobile also offers unlimited data service, for peace of mind.

Cons: T-Mobile's data network coverage is poor in rural areas. It's only now rolling out an "LTE" network, and it doesn't have access to the low frequencies where Verizon Wireless and AT&T run their wall-penetrating LTE networks. There's no option to share a data plan among many devices, but T-Mobile makes it relatively inexpensive to add a line to the plan: $10, which comes with 500 megabytes of data usage.

Bottom line: The price over two years for a 16-gigabyte iPhone 5 with unlimited calling, unlimited texting and 2.5 gigabytes of data usage per month, excluding taxes, is $2,020.

Verizon Wireless, AT&T

Last year, the two big guns in the wireless industry trotted out "shared data" plans that let a family tap into a common pool of data usage every month. They're betting on a future where phones will be just one of many devices connected to wireless networks.

Pros: The shared data plans make connecting tablets, laptops and mobile hotspots cheaper. Verizon has stellar coverage and the largest high-speed "LTE" network. AT&T has less coverage, but more than T-Mobile and Sprint, and it has a fast "4G" network in most places LTE isn't available.

Cons: For single phones, AT&T's and Verizon's prices are considerably higher than T-Mobile's ? you pay for that extra network coverage and reliability. Neither offers new customers unlimited data. The two-year contracts are complicated, with early termination fees and varying periods before you're eligible to buy a new phone at a subsidized price.

Bottom line: The price over two years for a 16-gigabyte iPhone 5 with unlimited calling, unlimited texting and 2 gigabytes to 3 gigabytes of data usage per month is $2,635, excluding taxes.

Sprint Nextel

The No. 3 wireless company has done the least to revamp its pricing plans ? they're pretty much the same they've been for the last five years.

Pros: Sprint has stuck to offering unlimited data plans, which is good for peace of mind. It sells smartphone service for as little as $35 per month through its Virgin Mobile subsidiary.

Cons: Unlimited data service is only good if the network is fast enough to serve up all the data you need, and Sprint's network is in a complicated transition period. Its "3G" service is very slow. It's complemented in places by Clearwire's "4G" network, and it's in the early stages of an "LTE" buildout. With unlimited data as the only option, Sprint-branded smartphone service isn't cheap. The two-year contracts are complicated, with early termination fees and varying periods before you're eligible to buy a new phone at a subsidized price.

Bottom line: The price over two years for 16-gigabyte iPhone 5 with unlimited calling, texting and data, excluding taxes, is $2,840.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/495d344a0d10421e9baa8ee77029cfbd/Article_2013-03-26-T-Mobile%20USA-Glance/id-3f96f80aac2d453fbc98565b7387e457

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Hong Kong court rejects Filipino maids' plea for residency

Domestic workers in Hong Kong have long been treated a notch below other foreign workers, and are told that admission into the country can never be for the purposes of settlement.

By Robert Marquand,?Staff writer / March 25, 2013

Sringatin, a member of a domestic workers union, cries outside the Court of Final Appeal in Hong Kong Monday, March 25, 2013. Hong Kong's top court ruled against two Filipino domestic helpers seeking permanent residency Monday, the final decision in a case that affects tens of thousands of other foreign maids in the southern Chinese financial hub.

Kin Cheung/AP

Enlarge

Hong Kong?s top court announced that foreigners can enter the city as maids and domestic helpers, but cannot expect to settle there as permanent residents.

Skip to next paragraph Robert Marquand

Staff writer

Over the past three decades, Robert Marquand has reported on a wide variety of subjects for?The Christian Science Monitor, including American education reform,?the wars in the Balkans, the Supreme Court, South Asian politics, and the oft-cited "rise of China." In the past 15 years he has served as the Monitor's bureau chief in Paris, Beijing, and New Delhi.?

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The verdict deals a blow to a huge contingent of Filipino maids and nannies ? estimated at some 300,000 females, usually unmarried and under 35 ? who make up a diaspora in Hong Kong. The domestic workers are increasingly seen as an indispensable part of the fast-paced city's social fabric, helping keep the Chinese family working and orderly in a highly competitive environment.

Yet sadly for the maids, today?s ruling reverses a lower court verdict that would have allowed the women?to seek residency.?Had it been upheld, the ruling would have been a breakthrough for the rights of domestic workers, who often complain of overwork, second-class status, and occasionally, abuse.

The system for foreign workers in Hong Kong is stratified. As CNN notes today:

While other foreign workers can apply for permanent residency after spending seven consecutive years in the Hong Kong Special Administrative Region, domestic helpers are excluded from the law.

Justice Ma wrote in his ruling that foreign domestic helpers are "told from the outset that admission is not for the purposes of settlement."

The ruling was greeted with disappointment by campaigners.

"It's very unfortunate and it's sad but in a way it will make us stronger as it highlights the social exclusion that foreign domestic workers face in Hong Kong," said Cynthia Tellez, General Manager of the?United Filipinos in Hong Kong.

In recent years the ubiquitous Filipino maid has become a staple part of Hong Kong culture. They are known for hard work, dignity, and efficiency. Collectively, they have built a kind of mini-civic society: They have their own postal system, often police themselves, have a variety of support groups, and even run ballots and campaigns for elections back home.

Most middle- and upper-echelon Hong Kong families hire a maid, and apartments usually include a tiny space as the maid?s quarters or abode.

For many years on Sundays, usually their only day off, Filipino nannies peacefully and colorfully gathered in central Hong Kong, along the main boulevard, past the city hall and the old Admiralty building, putting down blankets or chairs and pulling out lunch baskets, stretching out two-or three deep on a sidewalk in a line that often is a half-mile long.

Yet the right of maids to assemble has been under attack, and their overall legal status has been shrinking, as the city contemplates the costs (said to be $3 billion or more) of offering them the kinds of equal access that would involve education and other social services.

The South China Morning Post writes:

The judgment ends the right of abode saga started by a judicial review sought by Evangeline Vallejos Banao, a mother of five, who has worked in Hong Kong since 1986. She had argued that an immigration provision barring domestic workers from permanent residency was unconstitutional.

Mark Daly, a lawyer for Vallejos, said his client was ?speechless but calmly resigned and said ?no problem.?

Vallejos won a High Court ruling in 2011 granting her the right to request permanent residency status, denied to the city?s 300,000 foreign maids until then. The decision however was overturned later on a government appeal.

Source: http://rss.csmonitor.com/~r/csmonitor/globalnews/~3/AXPsqnhYOmQ/Hong-Kong-court-rejects-Filipino-maids-plea-for-residency

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Master These Oven Basics to Expand Your Cooking Repertoire

It's nothing to be ashamed about: you don't know how to use your oven. Maybe you make a batch of cookies when you want to feel accomplished (and full of cookies). Sometimes you burn them, and sometimes they fill the whole pan and you have a "cookie cake." But maybe you want more from your oven. You deserve more from your oven.

All those new kale chip recipes don't use a microwave. Slow braised lamb shanks aren't going to impress your friends if they come out of a box. Your oven has roasting and baking potential; you can braise, broil and dehydrate. You can crisp things and make things tender! Just give it a chance?get to know your oven.

Rainy weather (coming soon: April showers!) is the perfect time to start a lasting relationship with one of the best workhorses in the kitchen. Everybody loves an apartment that smells like chocolatey brownies or freshly-roasted chicken.

Here are the basic principles to a healthy relationship with your oven.

The racks in your oven move around. Most ovens come with more than one rack. Think about this before you preheat?moving a 400-degree metal rack is not fun. And make sure there is nothing in your oven when you start?many people keep other pots and pans in the oven because of space constraints. (Some people keep shoes and bags in there. Cooked shoes pose a lot of problems besides just finding some new kicks.)

Temperature is important. If you open your oven, you will lose heat and your oven will need time to recover. Try not to open it more than necessary. As you use your oven more, you will need to check things less as you get a feel for the recipes.

Heat rises. The top of your oven is hotter than the bottom. If you want something to cook slow and low ? think awesome pulled pork?put it at the bottom of the oven. If you want something to crisp quickly, put it at the top of your oven and keep an eye on it (think sweet potato fries for your pulled pork sandwiches). Most standard roasting and baking recipes are just fine sitting on the middle rack, where heat is the most consistent.

Ovens have a vent. It's usually in the middle of the oven, towards the back. It only takes one misplaced hand towel to start a fire.

Your food needs space. Just like when you cook on the stovetop, the food in your oven needs to have enough room to cook. If food is packed too close together, some parts will be crispy and delicious and some will be soggy and pathetic. This is also known as "don't crowd the pan." It will help your chicken get crispy skin, and your cookies bake evenly without sticking together.

Arm yourself with the right tools. One good sheet pan goes a long way. An oven mitt or pot holder will keep your hands free of burns. Also, cast iron pans are fantastic for oven use. Cast iron pans can be used instead of baking dishes?who says your lasagna or meatloaf needs to be rectangular? How are you going to make skillet cornbread if you don't have some rockin' cast iron?

All in all, ovens are not hard to use?you just need little basic knowledge and a can-do attitude. Before you know it, you'll be roasting and broiling like a champ.

Mastering Your Oven Food52

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Ready to put your new oven skills to the test? Check out Food52's Best-Ever Cocoa Brownies or Simplest Roast Chicken.

You can find writer William Widmaier delicately poaching eggs for cheddar grits, or elbow deep in a bag of Cheetos and Utz Crab Chips, but most of all, you can find him eating.

Image by Roboheart.

Want to see your work on Lifehacker? Email Tessa.

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/H6GP5KTRcOI/master-these-oven-basics-to-expand-your-cooking-repertoire

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Will Amanda Knox have to return to Italy for trial?

Knox is escorted to a hearing in 2008 (AP)

An Italian supreme court overturned the acquittal of Amanda Knox on Tuesday, ordering a review that could result in demanding that the 25-year-old return to Florence to stand trial again in the 2007 killing of her roommate.

Good luck.

Legal experts say there's little Italy can do to force Knox, who lives in Seattle, to return for the new hearings, and Knox's lawyers say there's no reason she would agree to do so.

?Merely because they have sent it back for revision does not mean that anything else will happen," Theodore Simon, one of Knox's lawyers, said in an interview with the "Today" show. "They will review it. They may simply affirm that there was a ?not guilty? before and it should remain the same. They may seek to take some further evidence, but nothing has really changed.?

[Related slideshow: The Amanda Knox trial]

Italian law cannot compel Knox to return to Italy for a new trial, although a court could declare her in contempt if she refused to appear. But even if that happened, the contempt charge would carry no additional penalties, the Associated Press said.

"If the court orders another trial, if she is convicted at that trial and if the conviction is upheld by the highest court, then Italy could seek her extradition," Carlo Dalla Vedova, another lawyer for Knox, told the news service. In that scenario, the United States would have to agree to extradite her.

That would seem unlikely since it violates the U.S. legal principle of double jeopardy preventing someone from being tried twice for the same crime. But Vedova told the New York Times it does not apply in this case because there had been no final ruling.

More from the AP:

It is unclear what would happen if she were convicted and sentenced to further prison time. It is possible Italy could seek her extradition, or that U.S. and Italian authorities could come to a deal that would keep her in the United States.

The new hearings will be held at an appellate court in Florence sometime later this year or early next year, the Italian court said.

In a statement released Tuesday, Knox called the court's decision "painful" since "the prosecution's theory of my involvement in Meredith's murder has been repeatedly revealed to be completely unfounded and unfair."

In 2011, Knox and Raffaele Sollecito, her former boyfriend, were acquitted in the murder of Meredith Kercher, a British student who was found dead in the Perugia, Umbria, apartment she shared with Knox, half naked with her throat slashed. Knox and Sollecito each spent four years in prison before the acquittal.

"The prosecution responsible for the many discrepancies in their work must be made to answer for them, for Raffaele's sake, my sake, and most especially for the sake of Meredith's family," Knox said. "Our hearts go out to them. No matter what happens, my family and I will face this continuing legal battle as we always have, confident in the truth and with our heads held high in the face of wrongful accusations and unreasonable adversity."

Knox's book about the case?"Waiting to Be Heard"?is due to be released next month.

Source: http://news.yahoo.com/blogs/lookout/amanda-knox-return-italy-stand-trial-180237891.html

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Mars Curiosity rover resumes science investigations

Mar. 25, 2013 ? NASA's Mars rover Curiosity has resumed science investigations after recovery from a computer glitch that prompted the engineers to switch the rover to a redundant main computer on Feb. 28.

The rover has been monitoring the weather since March 21 and delivered a new portion of powdered-rock sample for laboratory analysis on March 23, among other activities.

"We are back to full science operations," said Curiosity Deputy Project Manager Jim Erickson of NASA's Jet Propulsion Laboratory, Pasadena, Calif.

The powder delivered on Saturday came from the rover's first full drilling into a rock to collect a sample. The new portion went into the Sample Analysis at Mars (SAM) instrument inside the rover, which began analyzing this material and had previously analyzed other portions from the same drilling. SAM can analyze samples in several different ways, so multiple portions from the same drilling are useful.

The Rover Environmental Monitoring Station (REMS) is recording weather variables. The Radiation Assessment Detector (RAD) is checking the natural radiation environment at the rover's location inside Gale Crater.

Like many spacecraft, Curiosity carries a pair of main computers, redundant to each other, to have a backup available if one fails. Each of the computers, A-side and B-side, also has other redundant subsystems linked to just that computer. Curiosity is now operating on its B-side, as it did during part of the flight from Earth to Mars. The A-side was most recently used starting a few weeks before landing and continuing until Feb. 28, when engineers commanded a switch to the B-side in response to a memory glitch on the A-side. The A-side now is available as a backup if needed.

One aspect of ramping-up activities after switching to the B-side computer has been to check the six engineering cameras that are hard-linked to that computer. The rover's science instruments, including five science cameras, can each be operated by either the A-side or B-side computer, whichever is active. However, each of Curiosity's 12 engineering cameras is linked to just one of the computers. The engineering cameras are the Navigation Camera (Navcam), the Front Hazard-Avoidance Camera (Front Hazcam) and Rear Hazard-Avoidance Camera (Rear Hazcam). Each of those three named cameras has four cameras on it: two stereo pairs of cameras, with one pair linked to each computer. Only the pairs linked to the active computer can be used, and the A-side computer was active from before landing, in August, until Feb. 28.

"This was the first use of the B-side engineering cameras since April 2012, on the way to Mars," said JPL's Justin Maki, team lead for these cameras. "Now we've used them on Mars for the first time, and they've all checked out OK."

Engineers quickly diagnosed a software issue that prompted Curiosity to put itself into a precautionary standby "safe mode" on March 16, and they know how to prevent it from happening again. The rover stayed on its B-side while it was in safe mode and subsequently as science activities resumed.

Upcoming activities include preparations for a moratorium on transmitting commands to Curiosity from April 4 to May 1, while Mars will be passing nearly directly behind the sun from Earth's perspective. The moratorium is a precaution against possible interference by the sun corrupting a command sent to the rover.

NASA's Mars Science Laboratory project is using Curiosity and the rover's 10 science instruments to investigate the environmental history within Gale Crater, a location where the project has found that conditions were long ago favorable for microbial life. JPL, a division of the California Institute of Technology in Pasadena, manages the project for NASA's Science Mission Directorate in Washington.

More information about Curiosity is online at http://www.jpl.nasa.gov/msl , http://www.nasa.gov/msl and http://mars.jpl.nasa.gov/msl/ . You can follow the mission on Facebook at: http://www.facebook.com/marscuriosity and on Twitter at: http://www.twitter.com/marscuriosity .

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Story Source:

The above story is reprinted from materials provided by NASA/Jet Propulsion Laboratory.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

---

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/space_time/nasa/~3/ly7OxN8-WGU/130325111111.htm

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Old mice, young blood: Rejuvenating blood of mice by re-programming stem cells that produce blood

Mar. 25, 2013 ? The blood of young and old people differs. In an article published recently in the scientific journal Blood, a research group at Lund University in Sweden explain how they have succeeded in rejuvenating the blood of mice by reversing, or re-programming, the stem cells that produce blood.

Stem cells form the origin of all the cells in the body and can divide an unlimited number of times. When stem cells divide, one cell remains a stem cell and the other matures into the type of cell needed by the body, for example a blood cell.*

"Our ageing process is a consequence of changes in our stem cells over time," explained Martin Wahlestedt, a doctoral student in stem cell biology at the Faculty of Medicine at Lund University, and principal author of the article.

"Some of the changes are irreversible, for example damage to the stem cells' DNA, and some could be gradual changes, known as epigenetic changes, that are not necessarily irreversible, even if they are maintained through multiple cell divisions. When the stem cells are re-programmed, as we have done, the epigenetic changes are cancelled."**

The discovery that forms the basis for the research group's method was awarded the Nobel Prize in Medicine last year.

The composition of blood is one example of how it ages; blood from a young person contains a certain mix of B- and T-lymphocytes and myeloid cells.***

"In older people, the number of B- and T-lymphocytes falls, while the number of myeloid cells increases," said Martin Wahlestedt.

When an elderly person is affected by leukemia, the cancer often has its origin in the myeloid cells, of which the elderly have more. Being able to 're-start' the blood, as Martin and his colleagues have done in their studies on mice, therefore presents interesting possibilities for future treatment.

"There is a lot of focus on how stem cells could be used in different treatments, but all that they are routinely used for in clinical work today is bone marrow transplants for diseases where the blood and immune systems have to be regenerated," said Martin Wahlestedt, continuing:

"A critical factor that gives an indication of whether the procedure is going to work or not is the age of the bone marrow donor. By reversing the development of the stem cells in the bone marrow, it may be possible to avoid negative age-related changes."

Even if the composition of the blood in old and young mice is remarkably like that in young and elderly people, Martin Wahlestedt stressed that the science is still only at the stage of basic research, far from a functioning treatment. The research group is pleased with the results, because they indicate that it may not primarily be damage to DNA that causes blood to age, but rather the reversible epigenetic changes.

*About stem cells:

There are different types of stem cells. Embryonic stem cells, which can be extracted from an embryo at an early stage, have the capacity to develop into all types of cell. Stem cells are also found in adults, where they have more limited development potential, but can divide in principle an unlimited number of times. For example, blood cell-forming stem cells in bone marrow create all types of blood cell and stem cells in the brain create many different types of brain cell.

**About epigenetics:

Epigenetics is a term that has historically been used to describe the aspects of genetics that cannot be explained by the composition of an individual's DNA alone. For tissue and organs to form, a number of different types of cell must be developed. This happens through the activation and de-activation of different genes. When a cell formed in this manner then divides again, the gene expression can be maintained in the daughter cells. This is referred to as 'epigenetic inheritance'. The epigenetic mechanisms, or which genes are activated or de-activated, can be affected by factors such as age, chemicals, drugs and diet.

*** About the composition of blood:

B- and T-lymphocytes and myeloid cells are all white blood cells. Lymphocytes, as the name suggests, are particularly common in the lymphatic system. T-lymphocytes patrol the body and recognise a specific bacteria or virus. B-lymphocytes 'remember' old infections and can quickly be activated again if required. This memory capacity is the mechanism behind immunity. The myeloid cells belong to the blood system's 'big eaters' -- they neutralise damaged tissue, dead cells, and to a certain extent also bacteria.

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Story Source:

The above story is reprinted from materials provided by Lund University.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

---

Journal Reference:

1. M. Wahlestedt, G. L. Norddahl, G. Sten, A. Ugale, M.-A. Micha Frisk, R. Mattsson, T. Deierborg, M. Sigvardsson, D. Bryder. An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state. Blood, 2013; DOI: 10.1182/blood-2012-11-469080

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_science/~3/YJJ0QkbuMwQ/130325093659.htm

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Ford India apologizes over Berlusconi bondage ad

MUMBAI, India (AP) ? The Indian unit of Ford Motor Co. has apologized for advertisements decried as demeaning to women, including one depicting Italy's former Prime Minister Silvio Berlusconi with a trio of bound women in the trunk of a car.

A Ford India spokeswoman said Monday that the company is investigating whether anyone at the automaker ever saw the print ads, which were never used commercially but appeared over the weekend on a website showcasing creative advertising.

The ads caused an uproar online and came just after India passed a new law on violence against women following a fatal gang rape of a student on a bus that prompted mass protests and spotlighted the status of women in India.

Featuring Ford's logo, one ad showed three women bound and gagged in the trunk of an Indian-made compact, the Ford Figo, with Berlusconi smiling from the driver's seat alongside the slogan "Leave your worries behind with the Figo's extra-large boot."

Similar ads featured Paris Hilton apparently kidnapping reality television rivals the Kardashian sisters ? all three sisters tied up and one in a bikini ? and Formula One driver Michael Schumacher abducting his male racing competition.

Ford said Monday that it regrets the incident, calling the images "contrary to the standards of professionalism and decency within Ford."

The ads were created at advertising agency JWT India and appeared on the website adsoftheworld.com late Friday.

"Ford India Needs to Fire Its Advertising Execs," read a headline on a slate.com blog while Indians on Twitter reacted with posts like "Disgusting!" and "SHAME."

It was unclear Monday whether anyone at Ford India had approved or seen the ads.

"We take this very seriously and are reviewing approval and oversight processes, and taking necessary steps to ensure nothing like this ever happens again," Ford spokeswoman Sethi Deepti said by email.

JWT India's CEO also condemned the ads.

"These were made as posters by individuals. They have never been paid for and were not expected to be released," he told India's Economic Times newspaper.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2013-03-25-AS-India-Ford-Ad-Apology/id-b8850a39af6a47e5a8622dce4afcf19b

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